null

SMILES NC(=NCc1ccccc1C(F)(F)F)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=YGOCAMFQDLFNQK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50124907   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat GluN2B receptor after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8H20PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99GVPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX78TPPubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX78TPPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX78TPPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99GVPubMed