null

SMILES OC(=O)CC(Cc1ccc(OCCCNc2ccccn2)cc1)c1ccccc1

InChI Key InChIKey=IAMUMIBDQILHMZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50126594   

TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Binding affinity for alphaV-beta3 vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15K8PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity for alphaV-beta5 vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15K8PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for alphav/beta 3 vitronectin receptor in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15K8PubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of integrin alphabeta6 receptor expressed in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human intergrin alphavbeta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alphavbeta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of integrin alphavbeta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15K8PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human intergrin alphavbeta3 receptor by solid phase receptor assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed