null
SMILES N[C@@H](CC1=CCCCc2o[nH]c(=O)c12)C(O)=O
InChI Key InChIKey=HJEPOXZLPHUVFE-ZETCQYMHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50126764
Affinity DataKi: 2.57nMAssay Description:Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 173nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR3 flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 175nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR2(R) RNA-edited flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 199nMAssay Description:Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 202nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR4 flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 232nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR1 flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6(VCR) RNA-edited isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 6.70E+3nMAssay Description:Agonist activity at rat recombinant GluR4 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 580nMAssay Description:Agonist activity at rat recombinant GluR5(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at ConA-treated rat GluR5(Q) RNA-edited isoform expressed in Xenopus laevis oocytes assessed as glutamic acid-induced maximal curren...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+3nMAssay Description:Agonist activity at ConA-treated rat GluR1 flip isoform expressed in Xenopus laevis oocytes assessed as glutamic acid-induced maximal current by two-...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Agonist activity at rat recombinant GluR3 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 9.20E+4nMAssay Description:Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+4nMAssay Description:Agonist activity at rat recombinant GluR1 flip isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM ass...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 1 (GluR1o)More data for this Ligand-Target Pair
TargetGlutamate receptor(Xenopus laevis)
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 6.40E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing heteromeric Ionotropic glutamate receptor ionotropic kainate 2More data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 4 (GluR4o)More data for this Ligand-Target Pair
TargetGlutamate receptor 3(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 7.20E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR3o)More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor ionotropic kainate 1 (GluR5)More data for this Ligand-Target Pair