null

SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(cc1)C#N

InChI Key InChIKey=HIYYLOFJQXHPRU-OPXMRZJTSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131947   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131947(2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMed
TargetStromelysin-1(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131947(2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131947(2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMed
TargetCollagenase 3(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131947(2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131947(2-(4'-Cyano-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMed