null

SMILES C[C@@H](Cc1ccc(F)c(F)c1)C(=O)N[C@H]1N=C(c2ccc3OCOc3c2)c2ccccc2N(CC(N)=O)C1=O

InChI Key InChIKey=RXMOCYUYPYEZFP-QWXGXRTQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135583   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50135583((S)-N-((S)-5-Benzo[1,3]dioxol-5-yl-1-carbamoylmeth...)copy SMILEScopy InChI

Affinity DataIC50: 13nMAssay Description:In vitro inhibition of gamma secretase.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2FHQPubMed