null

SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(\CC(=O)NO)=C\C(C)C

InChI Key InChIKey=IHERVMJHCHNTKO-YJJOXIQCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135601   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Université de Reims-Champagne-Ardenne

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23ZXNPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Université de Reims-Champagne-Ardenne

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23ZXNPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université de Reims-Champagne-Ardenne

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23ZXNPubMed
TargetStromelysin-1(Homo sapiens (Human))
UMR/CNRS 6013

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of PKD2 ( assessed as residual activity at 1 uM ) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN952RPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université de Reims-Champagne-Ardenne

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23ZXNPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université de Reims-Champagne-Ardenne

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN952RPubMed
TargetStromelysin-1(Homo sapiens (Human))
UMR/CNRS 6013

Curated by ChEMBL
LigandPNGBDBM50135601((S,E)-N1-(3-(1H-indol-3-yl)-1-(methylamino)-1-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23ZXNPubMed