null

SMILES COc1ccc(cc1)C1(CNC(=O)c2ccc(NC(=O)c3ccco3)cc2)CCOCC1

InChI Key InChIKey=ZJZWZIXSGNFWQQ-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50136777   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human TNKS1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of human TNKS2 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of human TNKS1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human TNKS2 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PK7PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Maximum response (E max) against Histamine H1 receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Apparent pA2 value of compound at 10 nM concentration of mepyramine in guinea pig ileumMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136777(CHEMBL3753077)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of tankyrase in WNT3a-stimulated human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair