null

SMILES COc1ccc(C)cc1C(=O)NCCCCN1CCc2cc(OC)c(OC)cc2C1

InChI Key InChIKey=KOEMMHBJOHMMBF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137628   

TargetSigma intracellular receptor 2(Homo sapiens (Human))
Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to sigma-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92XBPubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  313nMAssay Description:Binding affinity at dopamine receptor D3 on Sf9 cells by [125I]-IABN displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H45PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  642nMAssay Description:Binding affinity at dopamine receptor D2 on Sf9 cells by [125I]-IABN displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H45PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£ degli Studi di Bari ALDO MORO

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain after 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56KQ5PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  3.08E+3nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92XBPubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  3.08E+3nMAssay Description:Displacement of 5-bromo-N-(4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl)-2,3-dimethoxybenzamide from sigma-1 receptor in mouse EMT6 cell me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P11KXPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  3.08E+3nMAssay Description:Binding affinity to sigma-1 opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3T54PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50137628(CHEMBL1830682 | CHEMBL60048 | N-(4-(6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataKi:  3.08E+3nMAssay Description:Inhibition of [3H]-(+)-pentazocine binding to Sigma opioid receptor of guiena pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H45PubMed