null

SMILES OP(O)(=O)C(Cc1cccnc1)P(O)(O)=O

InChI Key InChIKey=KZMOFWIRXNQJET-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50138725   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataKi:  7.40nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataKi:  34.8nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 34.2nMAssay Description:Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944DFPubMed
Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Aquifex aeolicus)
University of Illinois at Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Aquifex aeolicus IspH expressed in Escherichia coli BL21 (DE3) using HMBPP substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474DQ5PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 32.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B18PubMed