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SMILES N[C@@H]([C@H]1[C@@H](O)[C@@H]1C(O)=O)C(O)=O

InChI Key InChIKey=LGSORWLWDBCUMM-NTAGLIMJSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50138784   

TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor 3 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor 2 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  147nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+3nMAssay Description:Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed