null

SMILES Cl.Cl.CCNCc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1

InChI Key InChIKey=PEOJMACLKYXLPT-GJICFQLNSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139147   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. 40 Landsdowne Street, Cambridge, MA 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50139147(CHEMBL3765509)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P33HDPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. 40 Landsdowne Street, Cambridge, MA 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50139147(CHEMBL3765509)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P33HDPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceuticals International Co. 40 Landsdowne Street, Cambridge, MA 02139, United States.

Curated by ChEMBL
LigandPNGBDBM50139147(CHEMBL3765509)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P33HDPubMed