null

SMILES Brc1cnc2NC(=O)\C(=C/c3cccc(Oc4ccccc4)c3)c2c1

InChI Key InChIKey=ZAQPJTWHEWHPNC-ZDLGFXPLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142032   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of GST-fused TrkA (unknown origin) expressed in SF9 cells using H2N-RRRAAAEEIYGEINH2 peptide as substrate preincubated with ATP and Mg and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474FKSPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed