null
SMILES OP(O)(=O)C(F)(F)c1ccc(CC(Cc2ccc(cc2)C(F)(F)P(O)(O)=O)(C(=O)c2ccccc2)c2ccccc2)cc1
InChI Key InChIKey=IZDWSIZSMHRZPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50142311
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:In vitro inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair