null

SMILES COC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)C(=O)OCc1ccccc1

InChI Key InChIKey=PVVRPRVMELWOLG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142312   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142312(2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-mal...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VPMPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142312(2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-mal...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142312(2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-mal...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VPMPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142312(2,2-Bis-[4-(difluoro-phosphono-methyl)-benzyl]-mal...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VPMPubMed