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SMILES C(Oc1nn2c(nnc2c2ccccc12)-c1ccccc1)c1ccccn1

InChI Key InChIKey=QZDWWRKBDPYMIP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50143115   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959H0RPubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Binding affinity to recombinant human GABA-A alpha5beta3gamma2 receptor expressed in L(tk) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X0PPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.710nMAssay Description:Binding affinity to recombinant human GABA-A alpha3beta3gamma2 receptor expressed in L(tk) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X0PPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.710nMAssay Description:Binding affinity for human GABA-A receptor alpha3-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959H0RPubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959H0RPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959H0RPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143115(3-Phenyl-6-(pyridin-2-ylmethoxy)-[1,2,4]triazolo[3...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Binding affinity to recombinant human GABA-A alpha1beta3gamma2 receptor expressed in L(tk) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X0PPubMed