null

SMILES Fc1ccc(F)c(c1)N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1

InChI Key InChIKey=NWSVOKGXCYCZTI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50143664   

TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
Recordati s.p.a.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4P35PubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Lundbeck Research USA, Inc.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  0.950nMAssay Description:Binding affinity for human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445M0KPubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Recordati s.p.a.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  5.88nMAssay Description:Binding affinity constant against alpha-1B adrenergic receptor of guinea pig spleenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4P35PubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Lundbeck Research USA, Inc.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Binding affinity for rat Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445M0KPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Lundbeck Research USA, Inc.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity for human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445M0KPubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Recordati s.p.a.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  54nMAssay Description:Binding affinity for human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445M0KPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Lundbeck Research USA, Inc.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]-8-OH-DPAT) as radioli...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4P35PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Lundbeck Research USA, Inc.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Binding affinity for human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445M0KPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Recordati s.p.a.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  135nMAssay Description:In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]-prazosin in epididymal rat vas deferens.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4P35PubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Lundbeck Research USA, Inc.

Curated by ChEMBL
LigandPNGBDBM50143664(8-{2-[4-(2,5-Difluoro-phenyl)-piperazin-1-yl]-ethy...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity for human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445M0KPubMed