null

SMILES CCc1ccc2cc(cnc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C

InChI Key InChIKey=QUPSOTTWHXSAPW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148727   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148727(CHEMBL3770430 | US9518026, Example 64 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Inhibition of Toxoplasma gondii CDPK1 assessed as ATP consumption using (Biotin-C6-PLARTLSVAGLPGKK) as substrate after 90 mins by luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GXDPubMed
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148727(CHEMBL3770430 | US9518026, Example 64 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JN4US Patent
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
Boehringer Ingelheim (Canada) Ltd.

LigandPNGBDBM50148727(CHEMBL3770430 | US9518026, Example 64 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G91US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148727(CHEMBL3770430 | US9518026, Example 64 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G91US Patent
TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through its Center For Commercialization

US Patent
LigandPNGBDBM50148727(CHEMBL3770430 | US9518026, Example 64 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JN4US Patent