null

SMILES CC(C)(C)n1nc(c(C(N)=O)c1N)-c1cnc2cc(OC(F)(F)F)ccc2c1

InChI Key InChIKey=YJMHWCFTOAMRPN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148729   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148729(CHEMBL3770923 | US9518026, Example 66 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Toxoplasma gondii CDPK1 assessed as ATP consumption using (Biotin-C6-PLARTLSVAGLPGKK) as substrate after 90 mins by luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GXDPubMed
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148729(CHEMBL3770923 | US9518026, Example 66 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JN4US Patent
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
Boehringer Ingelheim (Canada) Ltd.

LigandPNGBDBM50148729(CHEMBL3770923 | US9518026, Example 66 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G91US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148729(CHEMBL3770923 | US9518026, Example 66 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G91US Patent
TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through its Center For Commercialization

US Patent
LigandPNGBDBM50148729(CHEMBL3770923 | US9518026, Example 66 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JN4US Patent