null

SMILES OC(=O)CN1C(=S)S\C(=C/c2cccc(OCc3ccccc3)c2)C1=O

InChI Key InChIKey=DHUZZZSRYGMFNN-YBEGLDIGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50149743   

TargetDolichyl-phosphate-mannose--protein mannosyltransferase 1(Candida albicans)
Oxfordshire OX14 4YS

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of Candida albicans protein mannosyl transferase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6B96PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)copy SMILEScopy InChI
Affinity DataIC50: 4.31E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7MKCPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7MKCPubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed