null

SMILES Fc1ccc2[nH]cc(CCNCCOc3cc(F)cc4CCCOc34)c2c1

InChI Key InChIKey=DUTGEQMBAUMVEL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50150093   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
ISF College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of 5HT transporter (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BWXPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  29.2nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Agonist activity at 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BWXPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
ISF College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 86.4nMAssay Description:Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150093(CHEMBL340873 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 235nMAssay Description:Inhibition concentration against 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RDWPubMed