null
SMILES CCCOc1cccc(Oc2cc3n(C)c(=O)n(C)c3cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)c1
InChI Key InChIKey=DYNNLYLIKZTWRT-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50150812
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
Affinity DataEC50: 830nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The alpha assay was used to assess the binding of the compounds of the application to TRIM24 at various concentrations. All compounds were added at c...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
The University of Texas MD Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair