null
SMILES CC(C(O)=O)c1ccc(c(F)c1)-c1cccc(OC(=O)NCc2ccccc2)c1
InChI Key InChIKey=PMXNCJIHYZGPJG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50153370
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain homogenates preincubated for 10 mins followed by addition of substrate measured after 30 mins by liqui...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ovine COX1 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic acid as substra...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic aci...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 3.00E+7nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna
US Patent
Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna
US Patent
Affinity DataIC50: 7.20E+3nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair