null

SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C#N)c2o1

InChI Key InChIKey=PCWJJXZGAQSUKE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50154045   

TargetEstrogen receptor beta(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C828S5PubMed
TargetEstrogen receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 423nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C828S5PubMed
TargetEstrogen receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 362nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C828S5PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataEC50:  5.5nMAssay Description:Displacement of [3H]-17beta-E2 from human ERbeta LBD by solid phase competitive radio ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5MCFPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C828S5PubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C828S5PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD40BTPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154045(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)copy SMILEScopy InChI
Affinity DataIC50: 411nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C828S5PubMed