null
SMILES [O-][N+](=O)\C=C\c1ccc2OCOc2c1
InChI Key InChIKey=KFLWBZPSJQPRDD-ONEGZZNKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50155928
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester
Curated by ChEMBL
The University of Manchester
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of NLRP3 in LPS stimulated mouse BMDM cells after 15 mins followed by addition of ATP by ELISA analysisMore data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester
Curated by ChEMBL
The University of Manchester
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse bone marrow derived macrophages preincubated for 15 mins followed by addition of ATP ...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester
Curated by ChEMBL
The University of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 ...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester
Curated by ChEMBL
The University of Manchester
Curated by ChEMBL
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion prein...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...More data for this Ligand-Target Pair