null

SMILES [O-][N+](=O)\C=C\c1ccc2OCOc2c1

InChI Key InChIKey=KFLWBZPSJQPRDD-ONEGZZNKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50155928   

TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50155928(3,4-Methylenedioxyb-Nitrostyrene | CHEMBL596380)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of NLRP3 in LPS stimulated mouse BMDM cells after 15 mins followed by addition of ATP by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZZMPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50155928(3,4-Methylenedioxyb-Nitrostyrene | CHEMBL596380)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse bone marrow derived macrophages preincubated for 15 mins followed by addition of ATP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0D7DPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50155928(3,4-Methylenedioxyb-Nitrostyrene | CHEMBL596380)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56PTRPubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))TBA
LigandPNGBDBM50155928(3,4-Methylenedioxyb-Nitrostyrene | CHEMBL596380)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2T24PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50155928(3,4-Methylenedioxyb-Nitrostyrene | CHEMBL596380)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN99FBPubMed
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))TBA
LigandPNGBDBM50155928(3,4-Methylenedioxyb-Nitrostyrene | CHEMBL596380)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2T24PubMed