null
SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(COc2cc(F)cc(c2)C#N)cc1-c1ccccc1
InChI Key InChIKey=QZDHBGDHOYXBBJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50156587
Affinity DataIC50: 9.96E+4nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2
Curated by ChEMBL
Université de Lille 2
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair