null

SMILES CCCn1c(I)nc(C[C@H](NC(=O)[C@@H]2CCC(=O)N2)C(=O)N2CCC[C@H]2C(N)=O)c1I

InChI Key InChIKey=ALUVNQTWFGBHRE-DRZSPHRISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50158400   

TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)copy SMILEScopy InChI
Affinity DataEC50:  780nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)copy SMILEScopy InChI
Affinity DataEC50:  350nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50158400(CHEMBL3780191)copy SMILEScopy InChI
Affinity DataEC50:  206nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8NKFPubMed