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SMILES [H][C@@]12C[C@@]([H])([C@H](C)[C@H](C1)Nc1ncnc3c4ccccn4nc13)C2(C)C

InChI Key InChIKey=YWDRLQJERKWZHT-CRWXNKLISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50160534   

TargetMetabotropic glutamate receptor 1(RAT)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160534(CHEMBL3786866)copy SMILEScopy InChI
Affinity DataIC50: 233nMAssay Description:Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R7JPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160534(CHEMBL3786866)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R7JPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160534(CHEMBL3786866)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R7JPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160534(CHEMBL3786866)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2R7JPubMed