null

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(Cl)c4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C

InChI Key InChIKey=XRZUOLFZBNANGA-RMKNXTFCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161879   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50161879(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086532PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50161879(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03KGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161879(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03KGPubMed