null

SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O

InChI Key InChIKey=CJUWBZDJMYYRDG-QFIPXVFZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 88 hits for monomerid = 50162007   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FBFPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CD8PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RT8PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M044ZXPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:Binding affinity at human GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XQ0PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Binding affinity for Monkey gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CD8PubMed
TargetGonadotropin-releasing hormone receptor(Rhesus macaque)
Neurocrine Biosciences, Inc

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Binding affinity at monkey GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XQ0PubMed
TargetGonadotropin-releasing hormone receptor(Rhesus macaque)
Neurocrine Biosciences, Inc

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from monkey GnRH receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RT8PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity for rat gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CD8PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity at rat GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XQ0PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from rat GnRH receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RT8PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Human gonadotropin-releasing hormone receptor stimulated calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CD8PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302NMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.03E+3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 11.4nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K115QMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24IMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24TMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from human wild type GnRHRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F309LMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 262nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290QMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284LMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111QMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203PMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284FMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 24.2nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118NMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189PMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203QMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290LMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W291FMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50162007((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749GSPubMed
Displayed 1 to 50 (of 88 total ) | Next | Last >>