null

SMILES CC(C)(Nc1nc(NO)nc(Nc2ccc3ncsc3c2)n1)c1ccccc1

InChI Key InChIKey=DOXJXXFTEWRETQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50162973   

TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of beta IRK tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of PDGF-R2 tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Insulin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetFibroblast growth factor receptor 1(Mus musculus)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of c-fms tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86TFPubMed