null

SMILES Nc1ncnc2nc(Sc3cc(Cl)ccc3Cl)[nH]c12

InChI Key InChIKey=MCNAGVNOAQTXRV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165314   

TargetHeat shock protein HSP 90-alpha(Mus musculus)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165314(8-(2,5-Dichloro-phenylsulfanyl)-9H-purin-6-ylamine...)copy SMILEScopy InChI
Affinity DataEC50:  8.51E+4nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WF6PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50165314(8-(2,5-Dichloro-phenylsulfanyl)-9H-purin-6-ylamine...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086532PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165314(8-(2,5-Dichloro-phenylsulfanyl)-9H-purin-6-ylamine...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WF6PubMed