null
SMILES CCn1c(nc2ccccc12)-c1nonc1N
InChI Key InChIKey=HCRQPXYLXXLKPT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50168588
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 960nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair