null
SMILES CN(CCN)c1ccc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)cc1NC(C)=O
InChI Key InChIKey=FBMJGDCKBKUMJF-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50172243
Affinity DataKon: 0.000250M-1s-1Assay Description:Binding affinity to His-tagged recombinant human CK2alpha assessed as dissociation rateMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
Therachem Research Medilab (India) Pvt. Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal 6 X His-tagged recombinant human full length Casein Kinase 2 alpha subunit expressed in Sf21 insect cells using BODIPY-FL-RR...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Dapk2 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Dyrk4 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Dyrk3 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Dyrk2 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Dyrk1b (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Dyrk1a (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk4 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk3 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk2 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Hipk1 (unknown origin) by quantitative PCRMore data for this Ligand-Target Pair
Affinity DataKd: 0.00600nMAssay Description:Binding affinity to His-tagged recombinant human CK2alpha (6 to 335 residues) after 50 to 116.7 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of full length N-terminal 6xHis-tagged recombinant human CK2alpha expressed in fall armyworm Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 a...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Dapk3 (unknown origin) at by quantitative PCRMore data for this Ligand-Target Pair