null

SMILES CC(C)(C)N1CCC(CC1)c1cc2n(-c3c(Cl)cccc3Cl)c(=O)ccc2c(n1)-c1ccc(F)cc1F

InChI Key InChIKey=AAVGYEROXZEBTI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175751   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50175751(7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMAssay Description:Inhibition of TNF alpha release in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4QH8PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50175751(7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of LPS stimulated TNF alpha release in whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4QH8PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50175751(7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4QH8PubMed