null

SMILES CC(C)(C)NCc1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H]1CCCCN1S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=BFWDXOBUPPVYOP-JYFHCDHNSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50182221   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Antagonist activity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CCTPubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN08K7PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN08K7PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CCTPubMed