null

SMILES Fc1ccc(Nc2ncnc3cnc(NC(=O)C#CCCN4CCCCC4)cc23)cc1Cl

InChI Key InChIKey=FKXXCQSSSCJHOZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182678   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50182678(CHEMBL205059 | N-[4-[(3-chloro-4-fluorophenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X96PubMed