null
SMILES CC(C)N(CC#CC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)C(C)C
InChI Key InChIKey=UMWZSZYWDMVROC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50182683
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair