null
SMILES Fc1ccc(Nc2ncnc3cnc(NC(=O)C#CCCN4CCOCC4)cc23)cc1Br
InChI Key InChIKey=DPNQFVJNRXPIOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50182688
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HER stimulated human erbB autophosphorylation in MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of erbB2 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of erbB1 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of erbB4 fusion protein expressed in baculovirus by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EGF stimulated human erbB1 autophosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair