null

SMILES CCOC(=O)C(=O)CC(=O)c1ccc2n(Cc3ccc(F)cc3)cc(C(=O)CC(=O)C(=O)OCC)c(=O)c2c1

InChI Key InChIKey=BLUWEGIFNAEAKR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50184346   

TargetIntegrase(Human immunodeficiency virus 1)
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50184346((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by plate-based electrochemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MRFPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50184346((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by gel-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MRFPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50184346((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity in presence of MgCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MRFPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50184346((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MnCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MRFPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Roma La Sapienza

Curated by ChEMBL
LigandPNGBDBM50184346((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity in presence of MnCl2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5MRFPubMed