null
SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=HUDQLWBKJOMXSZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50191854
Affinity DataKi: 20nMAssay Description:Binding affinity to purified recombinant human sEH by FRET-displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human soluble epoxide hydrolase using CMNPC as substrate after 5 mins by fluorescent assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
University of California-Davis
Curated by ChEMBL
University of California-Davis
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase by fluorescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human sEH by fluorescent assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
University of California-Davis
Curated by ChEMBL
University of California-Davis
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
University of California-Davis
Curated by ChEMBL
University of California-Davis
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant sEH using PHOME as substrate measured after 10 mins by fluorescent based assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
University of California-Davis
Curated by ChEMBL
University of California-Davis
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse recombinant sEH using PHOME as substrate measured after 10 mins by fluorescent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
University of California-Davis
Curated by ChEMBL
University of California-Davis
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse soluble epoxide hydrolaseMore data for this Ligand-Target Pair