null

SMILES NC(=N)c1ccc(CNC(=O)C2(Cc3ccccc3C2)NC(=O)[C@H](NCC(O)=O)C2CCCCC2)cc1

InChI Key InChIKey=UZAYUOPBAIRPKQ-XMMPIXPASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50193243   

TargetVitamin K-dependent protein C(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Competitive inhibition of human APC using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542Q3BPubMed
TargetCoagulation factor X(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Competitive inhibition of human coagulation factor 10a using S-2765 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542Q3BPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataKi: >1.90E+4nMAssay Description:Competitive inhibition of human coagulation factor 11a using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542Q3BPubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542Q3BPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human coagulation factor 11a using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542Q3BPubMed
TargetProthrombin(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human thrombin activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994VNPubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994VNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542Q3BPubMed