null

SMILES CNc1ncc2cc(ccc2n1)-c1cc(ccc1C)C(=O)Nc1ccc(OC2CCN(C)CC2)cc1

InChI Key InChIKey=IEIWHASYQUBSLR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194674   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194674(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of Jak3 by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194674(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194674(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194674(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed