null

SMILES CCN(CC)CC(=O)Nc1ccc(cc1NC(=O)c1ccc(C)c(c1)-c1ccc2nc(NC)ncc2c1)C(F)(F)F

InChI Key InChIKey=YGLITMMDQOZAHY-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194683   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194683(CHEMBL212953 | N-(2-(2-(diethylamino)acetamido)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of Jak3 by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194683(CHEMBL212953 | N-(2-(2-(diethylamino)acetamido)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 306nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194683(CHEMBL212953 | N-(2-(2-(diethylamino)acetamido)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MFDPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50194683(CHEMBL212953 | N-(2-(2-(diethylamino)acetamido)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair