null

SMILES CC(CO)N=C(N)c1c(Nc2ccc(Nc3ccccc3)cc2)s[nH]c1=O

InChI Key InChIKey=WHWRHSZXRYNDDO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50196392   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 266nMAssay Description:Inhibition of MEK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataEC50:  45nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of Chk2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N231JPubMed
TargetRibosomal protein S6 kinase beta-1/beta-2(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p70 S6 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 448nMAssay Description:Inhibition of Flt-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 265nMAssay Description:Inhibition of AuroraMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50196392(3-hydroxy-N-(2-hydroxy-1-methyl-ethyl)-5-(4-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 389nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38S5DPubMed