null

SMILES Cc1nnc(C)n1-c1ccc(O[C@@H]2[C@H](Cc3ccc(Cl)cc23)N2CC[C@@H](O)C2)c(Cl)c1

InChI Key InChIKey=PXZHZDNVYZAURZ-JZWVFAODSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196783   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi-Aventis Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50196783(CHEMBL3963951)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of CYP2D6 in pooled human hepatic microsomes using dextromethorphan substrate in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7CDJPubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Sanofi-Aventis Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50196783(CHEMBL3963951)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7CDJPubMed