null
SMILES CS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3c2cc(Cl)cc3Cl)N2CCNCC2)cc1
InChI Key InChIKey=OBAXAGJRJNTELH-PMACEKPBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50196810
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2D6 in pooled human hepatic microsomes using dextromethorphan substrate in presence of NADPHMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Sanofi-Aventis Deutschland GmbH
Curated by ChEMBL
Sanofi-Aventis Deutschland GmbH
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair