null
SMILES Oc1cccc2ccc(CN(CC#C)C(CCC3CCN(Cc4ccccc4)CC3)C#N)nc12
InChI Key InChIKey=DMOLFVGCLPCFQX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50197875
Affinity DataKi: 15nMAssay Description:Mixed-type inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Mixed-type inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 180 mins followed by substrate addition measured for 1 hr by hors...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 120 mins followed by substrate addition measured for 1 hr by hors...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant BuChE expressed in HEK293 cells using S-butyrylthiocholine iodide as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate measured for 1 hr by horse-radish peroxidase/amplex red-based fluorometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 240 mins followed by substrate addition measured for 1 hr by hors...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 60 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOB using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Indian Institute of Technology (Banaras Hindu University)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair