null

SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1c(O)cccc1Cl

InChI Key InChIKey=WQACVRFKZIYHIM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50198826   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50198826(4-(7-(2-chloro-6-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
In DepthDetails
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50198826(4-(7-(2-chloro-6-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32VGMPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50198826(4-(7-(2-chloro-6-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataKi:  1.62E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen, Inc.

US Patent
LigandPNGBDBM50198826(4-(7-(2-chloro-6-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB22PZUS Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen, Inc.

US Patent
LigandPNGBDBM50198826(4-(7-(2-chloro-6-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29024MWPubMed