null

SMILES O=C(CSC(c1ccccc1)c1ccccc1)N1CCN(CCCc2ccccc2)CC1

InChI Key InChIKey=GDQGBNUPTWWVQR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50199810   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Displacement of [3H]WIN35,428 from DAT in Sprague-Dawley rat brain membranes incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ05RVPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  47.2nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  47.2nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  47.2nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  469nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  773nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  773nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+3nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  1.43E+3nMAssay Description:The uptake assays were carried out 2 days after transfection. Prior to the experiment, the cells were washed once in 500 ul of uptake buffer (25 mM 4...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  9.32E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  9.32E+3nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain stem membranes incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ05RVPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  9.32E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  9.32E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  1.52E+4nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetTransporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  2.26E+4nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent
TargetTransporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  2.26E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7TRGUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

US Patent
LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  2.26E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47S7BUS Patent
TargetTransporter(Rattus norvegicus (rat))
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM50199810(CHEMBL3899193 | US10913711, Compound 11a | US11555...)copy SMILEScopy InChI
Affinity DataKi:  5.43E+4nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7Z87US Patent