null

SMILES OB(O)[C@@H]1CCCN1C(=O)CN1Cc2ccccc2C1=O

InChI Key InChIKey=SJCJCRMVAKSLPL-LBPRGKRZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50200723   

TargetProlyl endopeptidase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibitory constant against POPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NH1PubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibitiory constant against FAPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NH1PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataKi:  2.27E+4nMAssay Description:Inhibition constant against DPP-4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NH1PubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant His-tagged DPP8 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QM9PubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human recombinant His-tagged DPP9 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QM9PubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP2 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QM9PubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QM9PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4QM9PubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53N7WPubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200723((R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53N7WPubMed